PureWorks would like to recognize Dr. Walker and Jeff Walker for their recent efforts. They have been working hard in the laboratory to develop new, enhanced methods for testing PureWorks' products. Testing is critically important to insure the continued quality of our products. Their enhanced method is a new and improved approach that is faster and utilizes the newest and best analytical instrumentation available. There are multiple methods for testing "quats" but they are lengthy, expensive and are not as specific for benzethonium chloride.
In September, Jeff and Ed traveled to California and presented their new method at the International Meeting of the Association of Official Analytical Chemists (AOAC). The AOAC is the group that validates and approves official test methods that are recognized world wide in legal and regulatory applications. Attendees included scientists from various government agencies including FDA, EPA, CDC and others. Numerous scientists visited their poster and asked about the new method. Increased interest in benzethonium chloride's anti-cancer activity (announced by the National Cancer Institute last year) has spawned new interest in validated analytical methods for this ingredient. Numerous requests were received from other scientists to send them copies of the new method. Jeff and Ed anticipate publishing the new method in a peer-reviewed scientific journal in the near future.
The test is performed by HPLC (High Pressure Liquid Chromatograph), an instrument that separates, identifies, and quantifies the benzethonium chloride during the analysis. The new method also simultaneously determines seven other ingredients in the PureWorks products in less than 5 minutes! The new method has been successfully applied to monitor the manufacturing and stability of the PureWorks skin care products. It is essential to run such tests during manufacture of each of product. It is also important to test what happens to each ingredient over time, throughout the shelf-life of each product.
During the analysis procedure, the ingredients are separated by a unique solvent system being pumped at high pressure through a special chromatography column. As they exit the column, a highly-sensitive detection system measures their concentration. An example chromatogram of the separation of calibration standards shows the excellent separation. The area under each peak is proportional to its concentration. 
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